This is a loaded question.  The first question is how much time and effort do you want to put into it?  Generally the more time/effort you put into it, the more you will see per comic.

Going to a LCS (Local Comic Store) will generally see the least amount of money as they will offer pennies on the dollar as they want to resell for a profit.

Another option might be to try and sell on places like Craigslist.  You would likely see a higher return, but Craigslist has its pitfalls (i.e. security, etc).

You can list the comics for sale on ComicBookRealm.com and see if there are any takers.  We have a "Wheeling and Dealing" forum where you can post, or just add the comics to your sell list.  This is essentially like dealing with Craigslist except it is remote.

The "last" option would be to put the comics on eBay.  Selling higher value comics outside of a run will generally net more money than lumping them together.  Generally if you sell comics in a group you will earn less than selling them individually, however, the time and effort to sell goes way up.